B-hCD5L mice

C57BL/6JNifdc-Cd5ltm1(CD5L)Bcgen/Bcgen • 112516

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B-hCD5L mice

Catalog Number: 112516
Strain Name: C57BL/6JNifdc-Cd5ltm1(CD5L)Bcgen/Bcgen
Strain Background: C57BL/6JNifdc
NCBI gene ID: 922 (Human)
Aliases: AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA
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B-hCD5L mice

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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-hCD5L mice.
      The exons 1~6 of mouse Cd5l gene that encode the full-length protein were replaced by human CD5L exons 1~6 in B-hCD5L mice.

      Protein expression analysis

      Strain specific CD5L expression analysis in homozygous B-hCD5L mice by ELISA. Plasma were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hCD5L mice (H/H) analyzed by ELISA with species-specific CD5L ELISA kit. Mouse CD5L was detectable in wild-type mice (A). Human CD5L was exclusively detectable in homozygous B-hCD5L mice but not in wild-type mice (B).

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hCD5L mice] (Cat# 112516) was purchased from Biocytogen.