B-Tg(hIL8) mice

C57BL/6-Tg(RP11-9977L11)1Bcgen/Bcgen • 110832

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B-Tg(hIL8) mice

Product nameB-Tg(hIL8) mice
Catalog number110832
Strain nameC57BL/6-Tg(RP11-9977L11)1Bcgen/Bcgen
Strain backgroundC57BL/6N
NCBI gene ID3576 (Human)
AliasesGCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-Tg(hIL8) mice. The BAC containing the whole human IL8 genome sequence was randomly inserted into mouse genome in B-Tg(hIL8) mice.

      Protein expression analysis (F1)

      Strain specific IL8 expression analysis in B-Tg(hIL8) mice by ELISA. Serum were collected from wild-type C57BL/6 mice and B-Tg(hIL8) mice after stimulated with LPS in vivo, and analyzed by ELISA with species-specific IL8 ELISA kit. Human IL8 was exclusively detectable in B-Tg(hIL8) mice.

      Protein expression analysis (F2)

      Strain specific IL8 expression analysis in B-Tg(hIL8) mice by ELISA. Serum were collected from wild-type C57BL/6 mice and B-Tg(hIL8) mice after stimulated with LPS in vivo, and analyzed by ELISA with species-specific IL8 ELISA kit. Human IL8 was exclusively detectable in B-Tg(hIL8) mice.

      Protein expression analysis (F3)

      Strain specific IL8 expression analysis in B-Tg(hIL8) mice by ELISA. Serum were collected from wild-type C57BL/6 mice and B-Tg(hIL8) mice after stimulated with LPS in vivo, and analyzed by ELISA with species-specific IL8 ELISA kit. Human IL8 was exclusively detectable in B-Tg(hIL8) mice.