B-NDG hCSF1 mice

NOD.CB17-Prkdcscid Il2rgtm1Bcgen Csf1tm1(CSF1)Bcgen/Bcgen • 110591

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B-NDG hCSF1 mice

Product nameB-NDG hCSF1 mice
Catalog number110591
Strain nameNOD.CB17-Prkdcscid Il2rgtm1Bcgen Csf1tm1(CSF1)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID1435,3561,5591 (Human)
AliasesCD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1; CSF-1; MCSF; DNA-PKC; DNA-PKcs; DNAPK; DNAPKc; DNPK1; HYRC; HYRC1; IMD26; XRCC7; p350; MCSF; CD132; SCIDX1; DNA-PKC
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  • Phenotypic analysis

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      Protein expression analysis in spleen
      Strain specific CSF1 expression analysis in B-NDG mice and homozygous B-NDG hCSF1 mice by ELISA. Spleens were collected from B-NDG mice and homozygous B-NDG hCSF1 mice stimulated with 100 μg/mL LPS in vivo for 2 hrs (200 μL/mouse). Grinding supernatant from the spleens was analyzed by ELISA. Mouse CSF1 was only detectable in B-NDG mice. Human CSF1 was exclusively detectable in homozygous B-NDG hCSF1 mice. Values are expressed as mean ± SEM.
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-NDG hCSF1 mice] (Cat# 110591) was purchased from Biocytogen.