B-NDG hCSF1 mice

NOD.CB17-Prkdcscid Il2rgtm1Bcgen Csf1tm1(CSF1)Bcgen/Bcgen • 110591

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B-NDG hCRBN mice
B-NDG hCSF1/hTHPO mice

B-NDG hCSF1 mice

Product nameB-NDG hCSF1 mice
Catalog number110591
Strain nameNOD.CB17-Prkdcscid Il2rgtm1Bcgen Csf1tm1(CSF1)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID1435,3561,5591 (Human)
AliasesCSF-1, MCSF; CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1; DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350
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  • Phenotypic analysis

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      Protein expression analysis in spleen
      Strain specific CSF1 expression analysis in B-NDG mice and homozygous B-NDG hCSF1 mice by ELISA. Spleens were collected from B-NDG mice and homozygous B-NDG hCSF1 mice stimulated with 100 μg/mL LPS in vivo for 2 hrs (200 μL/mouse). Grinding supernatant from the spleens was analyzed by ELISA. Mouse CSF1 was only detectable in B-NDG mice. Human CSF1 was exclusively detectable in homozygous B-NDG hCSF1 mice. Values are expressed as mean ± SEM.