B-NDG hIL7/hIL15 mice

NOD.CB17-Prkdcscid Il2rgtm1Bcgen Il7tm1(IL7)Bcgen Il15tm1(IL15)Bcgen/Bcgen • 120612

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B-NDG hIL7/hIL15 mice

Product nameB-NDG hIL7/hIL15 mice
Catalog number120612
Strain nameNOD.CB17-Prkdcscid Il2rgtm1Bcgen Il7tm1(IL7)Bcgen Il15tm1(IL15)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID16168,16196,16186,19090 (Human)
AliasesIL-15; Il-7; hlb368; A630026I06Rik; gc; p64; [g]c; CD132; gamma(c); p460; scid; slip; DNAPK; DNPK1; HYRC1; XRCC7; dxnph; DOXNPH; DNAPDcs; DNA-PKcs
ApplicationPromote differentiation of human T cells and NK cells
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  • Phenotypic analysis

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      Protein expression analysis

      Strain specific IL7/IL15 expression analysis in homozygous B-NDG hIL7/hIL15 mice by ELISA. Serum were collected from WT and homozygous B-NDG hIL7/hIL15 (H/H) mice stimulated with poly(I:C) in vivo, and analyzed by ELISA with species-specific hIL7/IL15 ELISA kit. Human IL7/IL15 were exclusively detectable in homozygous B-NDG hIL7/ hIL15 but not WT B-NDG mice.

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-NDG hIL7/hIL15 mice] (Cat# 120612) was purchased from Biocytogen.