B-NDG hIL7/hIL15 mice

NOD.CB17-Prkdcscid Il2rgtm1Bcgen Il7tm1(IL7)Bcgen Il15tm1(IL15)Bcgen/Bcgen • 120612

B-NDG hIL7 mice
B-NDG HLA-A2.1 mice

B-NDG hIL7/hIL15 mice

Product nameB-NDG hIL7/hIL15 mice
Catalog number120612
Strain nameNOD.CB17-Prkdcscid Il2rgtm1Bcgen Il7tm1(IL7)Bcgen Il15tm1(IL15)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID3600,3574,3561,5591 (Human)
AliasesIL-15; IL-7; CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1; DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350
ApplicationPromote differentiation of human T cells and NK cells

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  • Phenotypic analysis

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      Protein expression analysis

      Strain specific IL7/IL15 expression analysis in homozygous B-NDG hIL7/hIL15 mice by ELISA. Serum were collected from WT and homozygous B-NDG hIL7/hIL15 (H/H) mice stimulated with poly(I:C) in vivo, and analyzed by ELISA with species-specific hIL7/IL15 ELISA kit. Human IL7/IL15 were exclusively detectable in homozygous B-NDG hIL7/ hIL15 but not WT B-NDG mice.