NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen • 111982
| Product name | B-NDG hALB mice |
|---|---|
| Catalog number | 111982 |
| Strain name | NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen |
| Strain background | B-NDG |
| NCBI gene ID | 213,3561,5591 (Human) |
| Aliases | HSA; FDAHT; PRO0883; PRO0903; PRO1341; P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1; HYRC; p350; DNAPK; DNPK1; HYRC1; IMD26; S473K; XRCC7; DNAPKc; DNA-PKC; DNA-PKcs |
| Application | Used for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life |
Strain specific ALB expression analysis in homozygous B-NDG hALB mice by ELISA. Serum was collected from B-NDG mice (+/+) and homozygous B-NDG hALB mice (H/H), and analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB was detectable in B-NDG mice (A). Human ALB was exclusively detectable in homozygous B-NDG hALB mice but not in B-NDG mice (B). In addition, human plasma was collected and assayed for human ALB expression levels as a reference (C).
