NOD.CB17-Prkdcscid Il2rgtm1Bcgen Hctm1(c645insTA)Bcgen/Bcgen • 110605
| Product name | B-NDG Hc mice |
|---|---|
| Catalog number | 110605 |
| Strain name | NOD.CB17-Prkdcscid Il2rgtm1Bcgen Hctm1(c645insTA)Bcgen/Bcgen |
| Strain background | B-NDG |
| NCBI gene ID | 15139,16186,19090 (Mouse) |
| Aliases | C5; He; C5a; Hfib2; gc; p64; [g]c; gamm; CD132; gamma(; gamma(c); DNA; DOX; dxn; DNA-; XRCC; p460; scid; slip; DNAPK; DNPK1; HYRC1; XRCC7; dxnph; DOXNPH; DNAPDcs;AI326420; AU019811; DNA-PKcs |
| Application | Antibody CDC function study |
Measurement of C5 inSerum
Measurement of total complement hemolytic activity in serum
Hemolytic capacity analysis in homozygous B-NDG Hc mice. Representative image demonstrating level of lysis of antibody-coated SRBC following incubation with diluted serum from human, C57BL6, B-NDG, or B-NDG Hc mice. Serum from human were used as positive complement control. Compared with B-NDG, the hemolytic ability of B-NDG Hc was significantly enhanced. The order of hemolytic capacity: B-NDG Hc ≥ C57BL/6 > B-NDG.
