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    Using humanzied B-hSIRPa/hCD47 mouse model to evaluate the efficacy and toxicity of CD47 and SIRPa antibodies

    December 31, 2019
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    Cancerimmunotherapy is one of the most promising research areasin the field of cancer therapy.Along the lO drug development process, production of mouse models forin vivo efficacy evaluation has always been a rate-limiting step. Therefore, We generated a novel humanized knock-in mouse toevaluate the efficacy of human lO antibodies.
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