SD-CAGtm1(icre)Bcgen/Bcgen • 211350
| Product name | B-CAG-iCre rats |
|---|---|
| Catalog number | 211350 |
| Strain name | SD-CAGtm1(icre)Bcgen/Bcgen |
| Strain background | SD |
| Official symbol | CAG promoter(a combination of artificially constructed promoter, which iscomposed of the early enhancer element of cytomegalovirus (CMV) and chicken beta-actin promoter) |
| Chromosome | 4 |
| Application | Function research of genes |
In this strain, Cre recombinase expression is under the control of CAG promoter. When crossed with a strain containing a loxP site-flanked sequence of interest, Cre-mediated recombination results in deletion of the floxed sequences in widespread cells or tissues of the offspring.
B-CAG-iCre rats were bred to B-CAG-tdTomato cKI rats, tdTomato were detected in the double-positive rats.
Immunofluorescent images of tdTomato and iCre in the main organs of double-positive rats. Arrows indicate the expression of iCre. Scale bar, 25 µm.
